Cytomegalovirus
(CMV) is a double-stranded DNA virus in the herpes virus family that can cause
disseminated or localized endorgan disease in patients with advanced
immunosuppression. Endorgan disease caused by CMV occurs in patients with
advanced immunosuppression, typically those with CD4 T-lymphocyte cell (CD4)counts <50 cells/mm3, who are either not receiving or have failed to respond
to antiretroviral therapy (ART).
Cytomegalovirus (CMV) is found universally
throughout all geographic and socioeconomic areas and infects an estimated 40%
to 100% of adults by the fourth decade of life. In addition, almost all
homosexual men with HIV are coinfected with CMV. In HIV-infected persons, CMV
can infect the GI tract, liver, lung, and nervous system. CMV can also infect
the retina and is the leading cause of blindness in the HIV population. Read more>>>>>>>>

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