The Institute of Medicine (IOM) emphases that
the future research should recognize priority reproductive health problems
identify effective interventions to address these problems, implement the
interventions. Pregnancy is the unique, relatively short reproductive event
with the far reaching consequences for the society. The central temporal organof pregnancy - placenta represents the intermediate “brain” during development,
performing functions of synthesis of neurotransmitters, which could not be
produced by under-developed fetal brain machinery and are required for maternal
brain protection.
The striking example of such function is the production of
serotonin by placenta: fetal brain is not capable to synthesize this molecule
and therefore relies on placental sources for function. Placenta responds to
maternal conditions, e.g. stress, under nutrition, obesity, alcohol consumption
though the mechanism of secretion of neuro-endocrine factors. From the other
hand reproductive hormones, such as progesterone derivativeallopregnanolone,
play an important in maternal cerebral neuroendocrine adaptation to pregnancy,
especially in decreasing stress responses during the second half of gestation. Read more>>>>>>>>>>>>>>>>>

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