The
prevalence of AN is increasing in western societies and its estimated
prevalence is 0.2-1.0%. Osteopenia is a common complication of this disorder,
leading to many negative consequences at a young age. Severe degrees of reduced
bone mass have been described in young adolescents even during the initial
stages of their illness.
A
significant amount of bone mass is accumulated during adolescence and diseases
that affect bone deposition during this time have persistent and severe effects.
The onset of anorexia nervosa (AN) during this critical time impedes the achievement
of pubertal bone mass. In addition, significant changes in body weight and
composition, pubertal development, and pubertal hormones, such as insulin-like
growth factor 1 (IGF-1), occur during AN may affect bone. Read more................
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