The
Institute of Medicine (IOM) emphases that the future research should recognize
priority reproductive health problems identify effective interventions to
address these problems, implement the interventions. Pregnancy is the unique,
relatively short reproductive event with the far reaching consequences for the
society. The central temporal organ of pregnancy - placenta represents the
intermediate “brain” during development, performing functions of synthesis of
neurotransmitters, which could not be produced by under-developed fetal brain
machineryand are required for maternal brain protection.
The striking example
of such function is the production of serotonin by placenta: fetal brain is not
capable to synthesize this molecule and therefore relies on placental sources
for function. Placenta responds to maternal conditions, e.g. stress,
undernutrition, obesity, alcohol consumption though the mechanism of secretion of
neuro-endocrine factors. From the other hand reproductive hormones, such as
progesterone derivativeallopregnanolone, play an important in maternal cerebral
neuroendocrine adaptation to pregnancy, especially in decreasing stress
responses during the second half of gestation. Read more>>>>>>>>>>>>>>>>>
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