Sunday, 6 August 2017

Aripiprazole-Induced Rabbit Syndrome: How Safe is Its Use in Adolescence?

Rabbit syndrome’ is an uncommon drug-induced extrapyramidal syndrome (EPS) characterised by rapid chewing movements similar to those made by rabbits, ordinarily faster and more regular than the orofacial tic of tardive dyskinesia; the tongue is spared. 

Aripiprazole
Aripiprazole
Aripiprazole is a D2 dopamine receptor partial agonist, 5HT1A partial agonist, and 5HT2A antagonist. Theoretically, it is an atypical antipsychotic with reduced EPS and hyperprolactinaemia. Aripiprazole is effective in treating schizophrenia and mania; also approved for use in various child and adolescent groups, autism-related irritability in children. The development of EPS and akathisia with aripiprazole was notable in most studies, though few studies showed development of tardive dyskinesia and neuroleptic malignant syndrome. Read More>>>>>>>>>>

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